EliSpot und LymeSpot revised

The EliSpot (enzyme-linked immunosorbent spot assay) measures the number of activated T lymphocytes that secrete cytokines (Interferon γ) against the respective antigen.

The EliSpot is a cellular test for determining an infection with Borrelia and various co-pathogens. This first generation of the enzymatic EliSpot in combination with the determination of CD3- and CD57-NK-cells provides important additional information about the infection.

The LymeSpot revised, provides information on the activity of the infection. This test can differentiate between active (specific effector cells) and latent (specific memory cells) infections. Due to the EliSpot, it is now possible to better evaluate infection, inflammation and autoimmune processes.

While the EliSpot is exclusively based on interferon γ production, the LymeSpot also determines the cytokine IL-2. According to the “traffic light principle”, the result of an active infection (mainly effector cells) is green in the test. This means that it is necessary for the therapist to treat the infection. If the relationship between γ interferon and interleukin-2 changes in the opposite direction, a latent disease can be assumed, which is shown in the laboratory test as a red marking of the cells (mainly memory cells). In this case, mandatory anti-infective treatment would no longer be indicated.


3 x 8.5 ml CPDA tubes (do not centrifuge, store at room temperature, do not cool)

Analytical test duration:

3 days

Accounting according to GOÄ:

EliSpot for Borrelia

  • 3 x digit 3694 (3 different antigen approaches) Factor 1.5
  • 1 x digit 4003 (lymphocyte isolation) factor 1.5

This results in a final price of 184.49 euros.

LymeSpot revised for Borrelia

  • 4 x digit 3694 (3 different antigen approaches) Factor 1.5
  • 1 x digit 3696 Factor 1.5
  • 1 x digit 4003 (lymphocyte isolation) factor 1,5

This results in a final price of 217.86 euros.

Please note that we charge a one-time price of 5.30 Euro for the test kit.

We offer further pathogen proofs in these test procedures, please take these from our Laboratory order form.

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